Posterior Reversible Encephalopathy Syndrome During Term Pregnancy- Case Report

 Dinesh Kumar Thapa1, Sunil Kumar Shah2, Raju Shrestha3, Niraj Keyal4, Suraj Thapaliya5

1Department of Neurosurgery, B&C Medical College Teaching Hospital, Birtamode, Jhapa, 

2Department of Obstetrics and Gynecology, B&C Medical College Teaching Hospital, Birtamode, Jhapa; 3Department of Anesthesia, B&C Medical College Teaching Hospital, Birtamode, Jhapa;

4Department of Critical Care Medicine, B&C Medical College Teaching Hospital, Birtamode, Jhapa; 

5Department of Radiodiagnosis, B&C Medical College Teaching Hospital, Birtamode, Jhapa

             DOI: https://doi.org10.3126/egn.v2i1.27470

Correspondence: 

Dr. Dinesh Kumar Thapa

Department of Neurosurgery

B&C Medical College Teaching Hospital, Birtamod, Jhapa, Nepal

E-mail: dineshkthapa@gmail.com

Phone: +977-98431234518

Abstract

Posterior reversible encephalopathy syndrome (PRES) or reversible posterior leukoencephalopathy syndrome (RPLS) is a rare clinic-neuro-radiologically diagnosed disease in pregnant women. Other clinical conditions causing PRES include hypertensive encephalopathy, renal failure, autoimmune disorders and treatment with immunosuppressant or cytotoxic medications. Uncommon clinical conditions include acute intermittent porphyria and cryoglobulinemia.This syndrome is also known as reversible posterior cerebral oedema syndrome or posterior leukoencephalopathy syndrome. Clinical features include headache, encephalopathy, seizures, cortical visual disturbances or blindness and parieto-occipital white matter changes on neuroimaging. We report a 21-year-old primigravida who presented to us at term pregnancy with seizures, altered sensorium, and hypertension, which was later diagnosed to be PRES and was successfully managed.

Key words: Hypertensive Encephalopathy, Posterior reversible encephalopathy syndrome, Pregnancy, Seizure.

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